If you ever wondered what the differences were between the major web browsers, this should help.
Lately, I've been using Firefox portable on a hard drive that I carry with me. At home, I use Google's Chrome on my computers. I started having problems with Firefox on my desktop, and it's memory leaks are just too much for my netbook to handle.
I never got the point to Opera. I like Safari on Mac, but until the Windows version gets a session manager, I'm not using it.
I use Internet Explorer only in extreme emergencies. I hate Internet Exploder. It's slow and clunky.